Dr. Adrienne C. Scheck is an Associate Professor in Neuro-Oncology Research and the Barrow Brain Tumor Research Center at the Barrow Neurological Institute in Phoenix, AZ. She is also an Adjunct Professor in the School of Life Sciences at Arizona State University and an Associate Investigator in the Cancer Biology Program at the Arizona Cancer Center of the University of Arizona. Dr. Scheck received her undergraduate degree from the University of Rochester in NY and her PhD from Rensselaer Polytechnic Institute in Troy, NY. After a postdoctoral fellowship in viral oncology at the Pennsylvania State College of Medicine in Hershey, Pennsylvania she moved to Memorial Sloan-Kettering Cancer Center to study AIDS-related dementia. She began her studies of brain tumors while at Sloan-Kettering and moved to the Barrow Neurological Institute in 1989.
Dr. Scheck is an acknowledged leader in the field of metabolic alteration as an adjunct to the standard of care to improve survival and minimize side effects for patients with malignant brain tumors. To this end, her laboratory has been studying the use of the therapeutic ketogenic diet (KD) for the treatment of malignant brain tumors. Their work has shown that the KD reduces the growth of malignant brain tumors through a wide variety of mechanisms, and it potentiates the effect of radiation and temozolomide chemotherapy. These preclinical studies have led to a clinical trial for patients with glioblastoma multiforme (www.clinicaltrials.gov NCT02046187). The second main goal of her research is to identify biomarkers that improve on the current methods of diagnosis and prognosis for this devastating disease.
Dr. Scheck has a strong interest in science education, and her laboratory team includes 7-10 high school students and college undergraduates. She directs the high school component of the Scientific Enrichment Program for Students, a program that places high school students in research laboratories around the Phoenix area.